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ISER/BrightFocus 2017 Glaucoma Symposium

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7:00am EDT

Breakfast Dining Room Registration Salons I-V Hallway

8:00am EDT

Keynote Lecture IV: Aqueous Humor Outflow and Beyond - Failure of Molecular Homeostasis in Glaucoma Emory AmphitheaterErnst Tamm MD

8:45am EDT

Platform Session VI: Young Investigators Emory AmphitheaterTatjana Jakobs MD • Jeremy Sivak PhD

8:46am EDT

THE BAX ACTIVATION MECHANISM REMAINS ACTIVE IN THE RGCs OF BAX DEFICIENT MICE FOR SEVERAL MONTHS FOLLOWING OPTIC NERVE CRUSH Emory AmphitheaterRyan J. Donahue

9:01am EDT

DIFFERENTIALLY EXPRESSED microRNAs IN THE AQUEOUS HUMOR OF PATIENTS WITH EXFOLIATION GLAUCOMA OR PRIMARY OPEN-ANGLE GLAUCOMA Emory AmphitheaterMichelle D. Drewry

9:17am EDT

REPETITIVE STRESS AND STRAIN DURING A CONTROLLED ELEVATION OF IOP INCREASES RETINAL GANGLION CELL DYSFUNCTION AND OPTIC NERVE INJURY Emory AmphitheaterHari Jayaram MA BMBCh PhD FRCSEd

9:33am EDT

INDUCIBLE MMP-3 EXPRESSION IN A STEROID-INDUCED MURINE MODEL OF GLAUCOMA Emory AmphitheaterJeffrey O'Callaghan BA

9:49am EDT

IMPAIRED CEREBROSPINAL FLUID FLOW INTO THE OPTIC NERVE IN GLAUCOMA Emory AmphitheaterEmily Mathieu BSc

10:05am EDT

Break and Poster Viewing Salons III-V + Garden Overlook

10:30am EDT

Platform Session VII: Glia Emory AmphitheaterMonica Vetter PhD • Yang Hu PhD

10:31am EDT

LINKING IOP ELEVATION TO INFLAMMATION THROUGH ATP Emory AmphitheaterClaire Mitchell PhD

10:50am EDT

MYELIN-RELATED PROTEIN ALTERATIONS IN THE OPTIC NERVE HEAD (ONH) OF NON-HUMAN PRIMATES (NHP) WITH EARLY EXPERIMENTAL GLAUCOMA (EEG) Emory AmphitheaterCheri Stowell PhD

11:10am EDT

DO MICROGLIA ENGULF 'LIVING' NEURONS? Emory AmphitheaterFelix Vazquez-Chona

11:30am EDT

FUNCTIONAL ROLE OF cAMP IN OXIDATIVE STRESS-INDUCED OPTIC NERVE HEAD ASTROCYTES Emory AmphitheaterWon-Kyu Ju

11:50am EDT

ASTROCYTE-PRODUCED LIPID MEDIATORS LXA4 and LXB4 PROTECT RETINAL GANGLION CELLS FROM ACUTE AND CHRONIC INJURY Emory AmphitheaterJeremy M. Sivak PhD

12:10pm EDT

DEBRIS IN THE OPTIC NERVE IN MOUSE DEVELOPMENT AND GLAUCOMA Emory AmphitheaterNicholas Marsh-Armstrong PhD

12:30pm EDT

Lunch Dining Room

1:45pm EDT

Platform Session VIII: Neurodegeneration Emory AmphitheaterClaire Mitchell PhD • Colleen McDowell PhD

1:46pm EDT

TARGETING THE FAS RECEPTOR IN A MOUSE MODEL OF GLAUCOMA PROVIDES SIGNIFICANT NEUROPROTECTION VIA INHIBITION OF INFLAMMATION AND APOPTOSIS Emory AmphitheaterAnitha Krishnan PhD

2:05pm EDT

OPTIC NERVE INJURY-INDUCED ER STRESS AND NEURODEGENERATION IN OPTIC NEUROPATHIES Emory AmphitheaterYang Hu MD PhD

2:25pm EDT

COMBINED DEFICIENCY OF JUN AND DDIT3 (CHOP) PROVIDE ADDITIVE, NEAR COMPLETE PROTECTION TO RETINAL GANGLION CELLS AFTER OPTIC NERVE INJURY Emory AmphitheaterRichard T. Libby PhD

2:45pm EDT

KINETICS OF BAX RECRUITMENT IN RGCS AFTER OPTIC NERVE DAMAGE Emory AmphitheaterRobert W. Nickells PhD

3:05pm EDT

IDENTIFICATION OF GSK-3 AND MAP4K4 FAMILY MEMBERS AS MEDIATORS OF PRIMARY RGC CELL DEATH Emory AmphitheaterDerek S. Welsbie MD PhD

3:25pm EDT

AUTOPHAGY IN THE NEURORETINA AND ANGLE REGIONA OF DBA/2J MICE Emory AmphitheaterPaloma B. Liton PhD

3:45pm EDT

Break and Poster Viewing Salons III-V + Garden Overlook

4:15pm EDT

Platform Session IX: Biomechanics Emory AmphitheaterClaude Burgoyne MD • Ian Sigal PhD

4:16pm EDT

IRIS IS MECHANICALLY STIFFER IN PATIENTS WITH OCCLUDABLE ANGLES POST LASER PERIPHERAL IRIDOTOMY Emory AmphitheaterRouzbeh Amini PhD

4:35pm EDT

BIOMECHANICS OF THE OPTIC NERVE HEAD OF HUMAN AND MOUSE EYES Emory AmphitheaterThao D. Nguyen PhD

4:55pm EDT

INCORPORATING PRE-EXISTING STRESS AND REALISTIC ANISOTROPIC MATERIAL PROPERTIES INTO EYE-SPECIFIC MODELS OF THE HUMAN OPTIC NERVE HEAD Emory AmphitheaterRafael Grytz PhD

5:15pm EDT

DIFFERENTIAL MIRNA AND MRNA EXPRESSION IN RESPONSE TO MECHANICAL STRAIN IN PRIMARY HUMAN TRABECULAR MESHWORK CELLS Emory AmphitheaterYutao Liu MD PhD

5:35pm EDT

Keynote Lecture V: High 'TEK' Solutions for Glaucoma Emory AmphitheaterSusan E. Quaggin MD

6:30pm EDT

Awards Reception and Gala Dinner Salons I-III

7:30pm EDT

Dinner Dining Room